The blood-tumor barrier (BTB) restricts the efficient delivery of anti-glioma drugs to cranial glioma tissues.Increased BTB permeability may allow greater delivery of the therapeutic agents.Increasing evidence has revealed that PIWI proteins and PIWI-interacting RNAs (piRNAs) play an important role in tumor progression.However, whether PIWI protein
OBJECTIVE: Anomalous origin of the left coronary artery from the right pulmonary artery (AOLCARPA), is a rare entity that is usually associated with other defects.Of the 20 cases of AOLCARPA reported in the literature, 14 (70%) had associations.We describe four patients with AOLCARPA without associated defects, but with a peculiar intramural aortic
Non-invasive brain stimulation is designed to target accessible brain regions that underlie many psychiatric disorders.One such method, transcranial magnetic stimulation (TMS), is commonly used in patients with treatment-resistant depression (TRD).However, for non-responders, the choice of an alternative therapy is unclear and often decided empiric
To Chase Rack examine Puritan nostalgia in the context of the Great Migration (1630s-40s), this paper analyzes the spiritual autobiography of the English tailor John Dane, in which he recollects his memories of leaving his family and wandering through Hertfordshire, as well as his return home and subsequent move to New England.By investigating how
The Task Segment Framework (TSF) is a tool to analyze full typing flows of translation Chase Rack tasks as keylogged with timestamps recorded for keydown, keyup, mouse clicks and moves, and actions performed in other applications.The TSF assumes that intentional pauses flag stretches where subjects concentrate on unrecorded cognitive processes such